Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27714519 | 0.90 | AVPR1A (0.41) | TPSAB1CNR1KDM1AAVPR1A | |
| SCHEMBL27714489 | 0.89 | TPSAB1 (0.49) | TPSAB1CNR1KDM1ASMN1; SMN2KDM4E | |
| SCHEMBL27735308 | 0.78 | TPSAB1 (0.52) | TPSAB1CNR1ALDH1A1HSD11B1GFER | |
| SCHEMBL3094980 | 0.77 | HSD11B1 (0.61) | HSD11B1AVPR1A | |
| SCHEMBL27714472 | 0.77 | MGLL (0.43) | MAPK1SMN1; SMN2KDM4EALDH1A1HSD11B1 | |
| SCHEMBL28775337 | 0.76 | LMNA (0.46) | TPSAB1CNR1KDM1AALDH1A1MEN1 | |
| SCHEMBL27714487 | 0.75 | MGLL (0.43) | CNR1SMN1; SMN2KDM4EALDH1A1HSD11B1 | |
| SCHEMBL27714540 | 0.73 | MEN1 (0.48) | TPSAB1CNR1KDM1ASMN1; SMN2MEN1 | |
| SCHEMBL27735250 | 0.73 | AVPR1A (0.55) | TPSAB1CNR1AVPR1A | |
| SCHEMBL27735364 | 0.73 | MEN1 (0.60) | TPSAB1CNR1MAPK1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101268067-A | Indol-3-yl-carbonyl-piperidine-benzimidazole derivatives as V1A receptor antagonists | HOFFMANN LA ROCHE (CH) | 2008-09-17 | — | — | CN | claimed |
| CN-101268067-A | Indol-3-yl-carbonyl-piperidine-benzimidazole derivatives as V1A receptor antagonists | HOFFMANN LA ROCHE (CH) | 2008-09-17 | — | — | CN | disclosed |