Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27756109 | 0.82 | TNKS (0.34) | MAPTSMN1; SMN2LMNAALDH1A1FGFR1 | |
| SCHEMBL27735510 | 0.81 | CASP1 (0.43) | L3MBTL1KMT2AMEN1MAPTLMNA | |
| SCHEMBL27756121 | 0.81 | ALDH1A1 (0.35) | L3MBTL1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL27756119 | 0.80 | TSHR (0.33) | KMT2AMEN1SMN1; SMN2NPC1LMNA | |
| SCHEMBL27735485 | 0.80 | NFE2L2 (0.40) | L3MBTL1PKMKMT2AMEN1MAPT | |
| SCHEMBL27735499 | 0.80 | MAPT (0.33) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL27735521 | 0.79 | WDR5 (0.39) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL2265909 | 0.76 | HTT (0.42) | L3MBTL1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL27735505 | 0.76 | NPC1 (0.32) | KMT2AMEN1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL755449 | 0.72 | ALDH1A1 (0.45) | L3MBTL1PKMKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101379048-B | Benzoxazines and related nitrogen-containing heterobicyclic compounds useful as mineralocorticoid receptor modulating agents | MITSUBISHI TANABE PHARMA CORP | 2012-03-21 | — | — | CN | disclosed |
| CN-101379048-A | Benzo oxazines and related nitrogen-containing heterobicyclic compounds useful as mineralocorticoid receptor modulating agents | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-03-04 | — | — | CN | disclosed |