Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | TNKS | O95271 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2265909 | 0.87 | HTT (0.42) | ALDH1A1HTTL3MBTL1MAPTTNKS | |
| SCHEMBL27735508 | 0.72 | L3MBTL1 (0.41) | ALDH1A1HTTL3MBTL1MAPTKMT2A | |
| SCHEMBL755966 | 0.68 | TNKS (0.45) | TNKSHSD11B1 | |
| SCHEMBL27756121 | 0.67 | ALDH1A1 (0.35) | ALDH1A1HTTL3MBTL1MAPTKMT2A | |
| SCHEMBL758334 | 0.66 | ALDH1A1 (0.41) | ALDH1A1HTTL3MBTL1MAPTKMT2A | |
| SCHEMBL27735521 | 0.66 | WDR5 (0.39) | ALDH1A1HTTMAPTKMT2AMEN1 | |
| SCHEMBL27735510 | 0.65 | CASP1 (0.43) | ALDH1A1L3MBTL1MAPTKMT2AMEN1 | |
| SCHEMBL754188 | 0.65 | MAPT (0.46) | ALDH1A1HTTL3MBTL1MAPTKMT2A | |
| SCHEMBL27735485 | 0.65 | NFE2L2 (0.40) | ALDH1A1HTTL3MBTL1MAPTKMT2A | |
| SCHEMBL3039656 | 0.61 | CASP1 (0.47) | ALDH1A1HTTL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984345-B9 | BENZOXAZINES AND RELATED NITROGEN-CONTAINING HETEROBICYCLIC COMPOUNDS USEFUL AS MINERALOCORTICOID RECEPTOR MODULATING AGENTS | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-03-21 | — | — | EP | disclosed |
| EP-1984345-B1 | BENZOXAZINES AND RELATED NITROGEN-CONTAINING HETEROBICYCLIC COMPOUNDS USEFUL AS MINERALOCORTICOID RECEPTOR MODULATING AGENTS | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-08-31 | — | — | EP | disclosed |