Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17137317 | 0.89 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTTDP1KMT2A | |
| SCHEMBL18093538 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTTDP1KMT2A | |
| SCHEMBL17318141 | 0.78 | LMNA (0.50) | ALDH1A1KDM4EMAPTTDP1KMT2A | |
| SCHEMBL17137206 | 0.76 | KMT2A (0.51) | ALDH1A1KDM4EMAPTTDP1KMT2A | |
| SCHEMBL27922288 | 0.74 | LMNA (0.47) | ALDH1A1KDM4EMAPTTDP1KMT2A | |
| SCHEMBL17137285 | 0.74 | LMNA (0.47) | ALDH1A1KDM4EMAPTTDP1KMT2A | |
| SCHEMBL18085631 | 0.71 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTTDP1KMT2A | |
| SCHEMBL27986526 | 0.71 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTTDP1KMT2A | |
| SCHEMBL135563 | 0.69 | F2 (0.53) | ALDH1A1KMT2AMEN1LMNAF2 | |
| SCHEMBL9738285 | 0.69 | F2 (0.53) | ALDH1A1KMT2AMEN1LMNAF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022094218-A1 | PROCESS FOR THE PREPARATION OF HETEROARYL-SUBSTITUTED SULFUR(VI) COMPOUNDS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2022-05-05 | — | — | WO | disclosed |
| CN-101328143-B | Fluorine-containing sulphoxide imines compounds, synthetic methods and uses sthereof | SHANGHAI INST ORGANIC CHEM | 2012-05-30 | — | — | CN | disclosed |
| CN-101328143-A | Fluorine-containing sulphoxide imines compounds, synthetic methods and uses sthereof | SHANGHAI INST ORGANIC CHEM (CN) | 2008-12-24 | — | — | CN | disclosed |