Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17137285 | 1.00 | LMNA (0.47) | LMNANPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL17318141 | 0.78 | LMNA (0.50) | LMNANPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL17137206 | 0.76 | KMT2A (0.51) | LMNANPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL27735833 | 0.74 | ALDH1A1 (0.47) | LMNANPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL17137317 | 0.73 | ALDH1A1 (0.49) | LMNANPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL18093538 | 0.71 | ALDH1A1 (0.43) | LMNANPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL22217081 | 0.70 | ALDH1A1 (0.42) | LMNANPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL12377380 | 0.70 | GAA (0.52) | LMNANPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL135563 | 0.69 | F2 (0.53) | LMNAKMT2AMEN1ALDH1A1F2 | |
| SCHEMBL9738285 | 0.69 | F2 (0.53) | LMNAKMT2AMEN1ALDH1A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373911-B | Single fluoro cyclopropanes compound and its preparation method and application | 中国科学院上海有机化学研究所 | 2016-12-14 | — | — | CN | disclosed |
| CN-104119246-A | Cyclopropane derivatives, and preparation method and application thereof | SHANGHAI INST ORGANIC CHEM | 2014-10-29 | — | — | CN | disclosed |
| CN-103373911-A | Monofluorocyclopropane compounds as well as preparation method and application for same | SHANGHAI INST ORGANIC CHEM | 2013-10-30 | — | — | CN | disclosed |