SCHEMBL2773663

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2774966	0.84	ADORA2B (0.58)	ADORA2BRAB9ANPC1SMN1; SMN2KMT2A
	SCHEMBL2775047	0.82	ADORA2B (0.54)	ADORA2BRAB9ANPC1SMN1; SMN2KMT2A
	SCHEMBL2773982	0.81	ADORA2B (0.52)	ADORA2BRAB9ANPC1SMN1; SMN2KMT2A
	SCHEMBL2774974	0.78	ADORA2B (0.49)	ADORA2BRAB9ANPC1SMN1; SMN2KMT2A
	SCHEMBL2777323	0.78	POLB (0.52)	ADORA2BKMT2AL3MBTL1ADORA3MEN1
	SCHEMBL6235404	0.77	SMN1; SMN2 (0.52)	ADORA2BRAB9ASMN1; SMN2KMT2AMAPT
	SCHEMBL2775955	0.76	ADRA1B (0.44)	MAPTALDH1A1HSD17B10ADRA1AADRA1B
	SCHEMBL16637307	0.75	HSD17B10 (0.52)	ADORA2BRAB9ASMN1; SMN2MAPTALDH1A1
	SCHEMBL2773897	0.74	ADORA2B (0.59)	ADORA2BRAB9ANPC1SMN1; SMN2KMT2A
	SCHEMBL2775229	0.72	AGTR1 (0.51)	ADORA2BKMT2AMAPTMEN1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.