Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8857470 | 0.84 | ALDH1A1 (0.39) | THRBALDH1A1TSHRSCN1ASCN2A | |
| SCHEMBL11821132 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TSHRCHRNB2CHRNB4 | |
| SCHEMBL14409179 | 0.77 | TSHR (0.42) | THRBTSHRL3MBTL1LMNAKDM4E | |
| SCHEMBL9646933 | 0.76 | CTSK (0.47) | THRBTSHRMEN1KMT2A | |
| SCHEMBL1038644 | 0.76 | TSHR (0.44) | ALDH1A1HSD17B10TSHRSMN1; SMN2TP53 | |
| SCHEMBL13051005 | 0.75 | THRB (0.49) | THRBALDH1A1HSD17B10TSHRCHRNB2 | |
| SCHEMBL7644507 | 0.75 | HCAR2 (0.41) | THRBALDH1A1TSHRCHRNB2CHRNB4 | |
| SCHEMBL9915775 | 0.74 | THRB (0.43) | THRBTSHRL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL6263245 | 0.73 | TSHR (0.40) | THRBALDH1A1TSHRCHRNB2CHRNB4 | |
| SCHEMBL4940542 | 0.73 | NPC1 (0.40) | THRBALDH1A1HSD17B10SCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101348536-B | Emulsion polymer comprising activators, process for preparation thereof and use thereof in two-component or multicomponent systems | EVONIK ROEHM GMBH | 2014-06-11 | — | — | CN | disclosed |
| CN-101343335-A | Two or more-component system cured by a redox initiator system with controllable working life, and the use thereof | EVONIK ROEHM GMBH (DE) | 2009-01-14 | — | — | CN | disclosed |