Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 5/20 | 0.51 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.47 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.47 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 4/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.46 |
| ▸ | RAF1 | P04049 | 2/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 2/20 | 0.45 |
| ▸ | PPIA | P62937 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27720113 | 0.93 | BRAF (0.48) | PNLIPEGFRERBB2RAF1NPC1 | |
| SCHEMBL27740976 | 0.88 | EGFR (0.51) | PNLIPEGFRERBB2RAF1GCGR | |
| SCHEMBL27720157 | 0.84 | MAPT (0.64) | PNLIPEGFRERBB2RAF1NPC1 | |
| SCHEMBL27720109 | 0.80 | MAPK14 (0.52) | EGFRHTR2AHTR2CKDRMET | |
| SCHEMBL27720100 | 0.80 | BRAF (0.63) | PNLIPEGFRERBB2RAF1NPC1 | |
| SCHEMBL27720129 | 0.80 | MEN1 (0.66) | EGFRERBB2RAF1NPC1RAB9A | |
| SCHEMBL27720161 | 0.80 | HTR2A (0.51) | EGFRHTR2AHTR2CKDRCSF1R | |
| SCHEMBL27720191 | 0.80 | CDK8 (0.55) | RAF1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL27720106 | 0.78 | RAF1 (0.51) | PNLIPEGFRERBB2RAF1NPC1 | |
| SCHEMBL27720155 | 0.77 | BRAF (0.64) | RAF1NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101298427-B | Diaryl urea compound and use thereof | GUANGZHOU INST BIOMED & HEALTH | 2012-03-21 | — | — | CN | disclosed |
| CN-101298427-A | Diaryl urea compound and use thereof | GUANGZHOU INST BIOMED & HEALTH (CN) | 2008-11-05 | — | — | CN | disclosed |