Thiophene

Thiophene

SCHEMBL27744508

O=[SH](=O)c1ccccc1.c1ccsc1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA5A P35218 1/20 0.33
CYP2E1 P05181 1/20 0.31
CYP2A6 P11509 1/20 0.31
CYP2B6 P20813 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiophene SCHEMBL25410291 0.81
Hydrochloric Acid SCHEMBL28762594 0.81 BBOX1 (0.35) CA2CA4CA5ACYP2A6
SCHEMBL29127374 0.81 BBOX1 (0.35) CA2CA4CA5ACYP2A6
SCHEMBL28801712 0.81 BBOX1 (0.35) CA2CA4CA5ACYP2A6
Acetic Acid SCHEMBL14764595 0.72 CES2 (0.42)
SCHEMBL28835548 0.72
Phosphoric Acid SCHEMBL28483871 0.72 CA2 (0.52) CA2CA4CA5A
Biphenyl SCHEMBL16872437 0.69 ALDH1A1 (0.60) CYP2E1CYP2A6CYP2B6
Biphenyl SCHEMBL8068963 0.69 ALDH1A1 (0.60) CYP2E1CYP2A6CYP2B6
Biphenyl SCHEMBL15656401 0.69 ALDH1A1 (0.60) CYP2E1CYP2A6CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103483260-B 1-aryl-5-alkylpyrazole derivative compounds, methods of making and methods of use thereof 梅瑞尔公司 2016-08-03 CN disclosed
CN-103396359-B Iminipyridine derivatives and they purposes as microbicide 先正达参股股份有限公司 2016-06-29 CN disclosed
CN-103483260-A 1-aryl-5-alkylpyrazole derivative compounds, methods of making and methods of use thereof AVENTIS AGRICULTURE 2014-01-01 CN disclosed
CN-103396359-A Iminipyridine derivatives and uses thereof as microbiocides SYNGENTA PARTICIPATIONS A G 2013-11-20 CN disclosed
CN-101657423-B Iminopyridine derivatives and their use as microbicides SYNGENTA PARTICIPATIONS AG 2013-11-06 CN disclosed
CN-101453897-B Low odor, low volatility solvent for agricultural chemicals HUNTSMAN SPEC CHEM CORP 2013-10-30 CN disclosed
CN-101511795-B 1-aryl-5-alkylpyrazole derivative compounds, methods of making and methods of use thereof AVENTIS AGRICULTURE 2013-09-18 CN disclosed
CN-101827837-A Condensed anthranilamide insecticides SYNGENTA PARTICIPATIONS AG 2010-09-08 CN disclosed
CN-101743237-A condensed anthranilamide insecticides SYNGENTA PARTICIPATIONS AG 2010-06-16 CN disclosed
CN-101657423-A Iminopyridine derivatives and their use as microbicides SYNGENTA LTD 2010-02-24 CN disclosed
CN-101573355-A N-cyanoalkylanthranilamides as insecticides SYNGENTA PARTICIPATIONS AG (CH) 2009-11-04 CN disclosed
CN-101453897-A Low odor, low volatility solvent for agricultural chemicals HUNTSMAN SPEC CHEM CORP STERN (US) 2009-06-10 CN disclosed