Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211938 | 0.84 | LMNA (0.54) | MLYCDHPGDNPSR1KMT2AGAA | |
| SCHEMBL7212094 | 0.83 | CYP1A2 (0.57) | MLYCDHPGDKMT2AMEN1KDM4E | |
| SCHEMBL6656313 | 0.82 | NPC1 (0.59) | HPGDKMT2AGAAHSD17B10 | |
| SCHEMBL11349126 | 0.80 | RAB9A (0.56) | MLYCDHPGDNPSR1KMT2AGAA | |
| SCHEMBL26031477 | 0.79 | NAMPT (0.50) | MLYCDHPGDNPSR1CYP1A2CYP2D6 | |
| SCHEMBL3037389 | 0.78 | MEN1 (0.56) | MLYCDHPGDNPSR1KMT2AGAA | |
| SCHEMBL6196126 | 0.78 | NPC1 (0.57) | — | |
| SCHEMBL6196129 | 0.78 | NPC1 (0.57) | — | |
| SCHEMBL5663152 | 0.76 | MLYCD (0.40) | MLYCDHPGDNPSR1KMT2AMEN1 | |
| SCHEMBL7715145 | 0.76 | FOLH1 (0.50) | HPGDKMT2AMEN1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101472916-A | Chemical compounds | ASTRAZENECA AB (SE) | 2009-07-01 | — | — | CN | disclosed |