Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | NEK1 | Q96PY6 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8285019 | 1.00 | ALPL (0.44) | ALPLALPIALPGMEN1KMT2A | |
| SCHEMBL6278630 | 0.84 | ATP1A1 (0.42) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8284242 | 0.82 | ALDH1A1 (0.53) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL14452548 | 0.82 | ALDH1A1 (0.53) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8285914 | 0.82 | ALDH1A1 (0.53) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13096521 | 0.80 | L3MBTL1 (0.47) | MEN1KMT2ACRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL5910308 | 0.80 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8285916 | 0.80 | L3MBTL1 (0.47) | MEN1KMT2ACRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL8284256 | 0.80 | PKM (0.41) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL27745176 | 0.80 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058892-A1 | PYRAZOLO [3,4-B] PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-06-30 | — | — | WO | disclosed |