SCHEMBL27746341

SCHEMBL27746341

NC[SiH](N)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 2/20 0.39
TAAR1 Q96RJ0 8/20 0.36
HTR2A P28223 3/20 0.36
CYP2A6 P11509 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HRH1 P35367 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
THPO P40225 1/20 0.32
MAOA P21397 1/20 0.32
TSHR P16473 1/20 0.32
DPP4 P27487 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8194005 0.76 LOXL2 (0.32) LOXL2TSHR
SCHEMBL6051822 0.69
SCHEMBL9455023 0.69 TDP1 (0.39) LOXL2TAAR1SMN1; SMN2CYP1A2CYP3A4
SCHEMBL2004810 0.65
SCHEMBL28935854 0.65
SCHEMBL3482296 0.61 ALDH1A1 (0.40) CYP2A6SMN1; SMN2CYP3A4TSHR
SCHEMBL38902 0.61 ALDH1A1 (0.40) CYP2A6SMN1; SMN2CYP3A4TSHR
Hydrochloric Acid SCHEMBL6558614 0.61 CALM1 (0.35) LOXL2TSHR
SCHEMBL704630 0.61 CALM1 (0.35) LOXL2TSHR
SCHEMBL706709 0.61 CALM1 (0.35) LOXL2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101328189-A Preparation of bis(N,N-diethyl) aminomethyl phenyl silane UNIV HANGZHOU NORMAL (CN) 2008-12-24 CN claimed
CN-102159596-B Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO LTD 2014-05-07 CN disclosed
CN-101328189-B Preparation of bis(N,N-diethyl) aminomethyl phenyl silane UNIV HANGZHOU NORMAL 2010-12-08 CN disclosed
CN-101328189-A Preparation of bis(N,N-diethyl) aminomethyl phenyl silane UNIV HANGZHOU NORMAL (CN) 2008-12-24 CN disclosed