Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27471844 | 0.85 | RAB9A (0.43) | KMT2AMEN1SLC6A4HPGDRAB9A | |
| SCHEMBL3328392 | 0.81 | CYP4F2 (0.44) | KMT2AMEN1HPGDRAB9AALOX15 | |
| SCHEMBL28781871 | 0.81 | ALDH1A1 (0.44) | KMT2AMEN1RAB9A | |
| SCHEMBL28015642 | 0.81 | CES2 (0.45) | KMT2AMEN1PARP1KEAP1KCNN4 | |
| SCHEMBL27866349 | 0.79 | MEN1 (0.39) | KMT2AMEN1PARP1KEAP1HPGD | |
| SCHEMBL27427445 | 0.79 | KEAP1 (0.48) | KMT2AMEN1PARP1KEAP1KCNN4 | |
| SCHEMBL20573251 | 0.78 | CHRM3 (0.42) | PTGDR2 | |
| SCHEMBL28896366 | 0.78 | ALDH1A1 (0.42) | KMT2AMEN1HTR2ASLC6A4KCNH2 | |
| SCHEMBL27524200 | 0.78 | FFAR1 (0.46) | KMT2AMEN1PARP1FFAR1FFAR4 | |
| SCHEMBL28016662 | 0.77 | CCR5 (0.36) | KMT2AMEN1HTR2AKCNH2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108290881-A | Therapeutic compounds and methods of use thereof | 健泰科生物技术公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-104968654-B | Substituted 2-aminopyridine albuminoid kinase inhibitor | CHIA TAI TIANQING PHARMACEUTICAL GROUP Co.,Ltd. (CN) | 2018-06-01 | — | — | CN | disclosed |
| CN-104797555-B | N-substituted benzamides and methods of use thereof | 基因泰克公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-104797555-A | N-substituted benzamides and methods of use thereof | GENENTECH INC | 2015-07-22 | — | — | CN | disclosed |
| CN-101970420-B | Oxadiazole derivatives | MERCK SERONO SA | 2014-09-24 | — | — | CN | disclosed |
| CN-101472888-B | Optically pure flavone derivatives for treating proliferative disorders and process for preparing same | PIRAMAL LIFE SCIENCES LTD | 2014-02-26 | — | — | CN | disclosed |
| CN-101472888-A | Optically pure flavone derivatives for treating proliferative disorders and process for preparing same | PIRAMAL LIFE SCIENCES LTD (IN) | 2009-07-01 | — | — | CN | disclosed |