Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321709 | 1.00 | CA2 (0.38) | CA2CA1CA9 | |
| SCHEMBL13053720 | 1.00 | CA2 (0.38) | CA2CA1CA9 | |
| SCHEMBL12712866 | 1.00 | CA2 (0.38) | CA2CA1CA9 | |
| SCHEMBL22149279 | 0.91 | CA1 (0.33) | CA2CA1CA9 | |
| SCHEMBL22149284 | 0.91 | CA1 (0.33) | CA2CA1CA9 | |
| SCHEMBL7152300 | 0.80 | CA2 (0.44) | CA2CA1CA9 | |
| SCHEMBL13954220 | 0.79 | CA1 (0.32) | CA2CA1CA9 | |
| SCHEMBL13053771 | 0.77 | CA1 (0.34) | CA2CA1CA9 | |
| SCHEMBL11126008 | 0.76 | CA2 (0.41) | CA2CA1CA9 | |
| SCHEMBL328620 | 0.76 | CA2 (0.41) | CA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133881-B2 | \"street-safe\" version of a controlled substance such as fentanyl, levorphanol, methadone, oxycodone, morphine, amphetamine, methylphenidate that permits the therapeutically beneficial effects while reducing euphoric effects that lead to substance abuse | SHIRE LLC (US) | 2012-03-13 | — | — | US | disclosed |
| US-20090036553-A1 | DENDRITIC ENCAPSULATION OF ACTIVE AGENTS | SHIRE LLC (US) | 2009-02-05 | — | — | US | disclosed |
| US-7438900-B2 | Dendritic encapsulation of active agents | SHIRE LLC (US) | 2008-10-21 | — | — | US | disclosed |
| US-20070197451-A1 | Carbohydrate conjugates to prevent abuse of controlled substances | SHIRE LLC | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036553-A1 | DENDRITIC ENCAPSULATION OF ACTIVE AGENTS | DDOST, CLEC4M, SDCBP | CA2 3590/4885CA1 1698/4885CA9 2818/4885 |
| US-20070197451-A1 | Carbohydrate conjugates to prevent abuse of controlled substances | CES2, FUT6, FUT5 | CA2 1020/4885CA1 322/4885CA9 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.