Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | PRKCZ | Q05513 | 9/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | PRKCI | P41743 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689305 | 0.93 | ALDH1A1 (0.70) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 | |
| SCHEMBL689612 | 0.81 | HSD17B10 (0.77) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 | |
| SCHEMBL8288638 | 0.81 | PRKCZ (0.72) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 | |
| SCHEMBL1190649 | 0.81 | PRKCZ (0.80) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 | |
| SCHEMBL8288636 | 0.81 | ALDH1A1 (0.70) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 | |
| SCHEMBL8289775 | 0.80 | ALDH1A1 (0.69) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 | |
| SCHEMBL689025 | 0.80 | PRKCZ (0.73) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 | |
| SCHEMBL689202 | 0.80 | PRKCZ (0.73) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 | |
| SCHEMBL3974980 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 | |
| SCHEMBL689452 | 0.79 | PRKCZ (0.80) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101351453-A | Heterocyclic amide compound and use thereof | TAKEDA PHARMACEUTICAL (JP) | 2009-01-21 | — | — | CN | disclosed |