Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11238778 | 0.98 | ALDH1A1 (0.61) | ALDH1A1TDP1CYP3A4TSHRTEAD4 | |
| SCHEMBL2774995 | 0.88 | CYP1A1 (0.52) | ALDH1A1TDP1CYP3A4TSHRMAOB | |
| SCHEMBL112595 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL9144824 | 0.83 | CYP3A4 (0.55) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| Hydrochloric Acid SCHEMBL4372246 | 0.83 | CYP3A4 (0.55) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL9487306 | 0.81 | ALDH1A1 (0.70) | ALDH1A1TDP1CYP3A4TSHRTEAD4 | |
| SCHEMBL7225718 | 0.81 | ALDH1A1 (0.70) | ALDH1A1TDP1CYP3A4TSHRTEAD4 | |
| SCHEMBL126339 | 0.81 | ALDH1A1 (0.70) | ALDH1A1TDP1CYP3A4TSHRTEAD4 | |
| SCHEMBL65211 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TDP1CYP3A4TSHRTEAD4 | |
| SCHEMBL2013073 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TDP1CYP3A4TSHRTEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912506-A | 1, 2-Diaza-5-carboxamide compound, preparation method and application thereof | 沈阳药科大学 | 2025-05-02 | — | — | CN | disclosed |
| WO-2008045671-A1 | MATRIX METALLOPROTEASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-04-17 | — | — | WO | disclosed |
| US-20080085893-A1 | MATRIX METALLOPROTEASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-04-10 | — | — | US | disclosed |
| US-4329365-A | DIPHENYL ETHERS | BURROUGHS WELLCOME CO. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4198407-A | Substituted 2-phenyl-1,2,4-triazine-3,5(2H,4H)-diones, and coccidiostatic agents containing same | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085893-A1 | MATRIX METALLOPROTEASE INHIBITORS | MMP3, MMP7, MMP9 | ALDH1A1 341/4885TDP1 1237/4885CYP3A4 2201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.