Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.65 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29485894 | 0.76 | NPC1 (0.57) | ALDH1A1RAB9AHCAR2NPC1MAPT | |
| SCHEMBL265422 | 0.76 | NPC1 (0.57) | ALDH1A1RAB9AHCAR2NPC1MAPT | |
| SCHEMBL8194585 | 0.75 | LMNA (0.64) | SMN1; SMN2TAS1R3TAS1R1ALDH1A1KMT2A | |
| SCHEMBL8194587 | 0.75 | LMNA (0.64) | SMN1; SMN2TAS1R3TAS1R1ALDH1A1KMT2A | |
| SCHEMBL18985301 | 0.74 | RAB9A (0.74) | SMN1; SMN2ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL18985299 | 0.74 | RAB9A (0.74) | SMN1; SMN2ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL7448092 | 0.74 | TAS1R3 (0.63) | SMN1; SMN2TAS1R3TAS1R1ALDH1A1KMT2A | |
| SCHEMBL8086204 | 0.74 | TAS1R3 (0.63) | SMN1; SMN2TAS1R3TAS1R1ALDH1A1KMT2A | |
| SCHEMBL28965883 | 0.74 | TAS1R3 (0.63) | SMN1; SMN2TAS1R3TAS1R1ALDH1A1KMT2A | |
| SCHEMBL7448095 | 0.74 | TAS1R3 (0.63) | SMN1; SMN2TAS1R3TAS1R1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101365681-B | Iminopropene compound and use thereof | SUMITOMO CHEMICAL CO | 2013-01-02 | — | — | CN | disclosed |
| CN-101365681-A | Iminopropene compound and use thereof | SUMITOMO CHEMICAL CO (JP) | 2009-02-11 | — | — | CN | disclosed |