Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 12/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2779821 | 0.90 | CCR1 (0.47) | CCR1KCNH2TSHREPHX2HMOX1 | |
| SCHEMBL2777506 | 0.86 | ALDH1A1 (0.44) | CCR1KCNH2TSHRLMNAEPHX2 | |
| SCHEMBL2776101 | 0.85 | CCR1 (0.43) | CCR1KCNH2TSHRLMNAEPHX2 | |
| Hydrochloric Acid SCHEMBL6518828 | 0.83 | DPP4 (0.47) | LMNAEPHX2HMOX1USP30DPP4 | |
| SCHEMBL2775696 | 0.83 | EPHX2 (0.53) | CCR1KCNH2TSHRLMNAEPHX2 | |
| SCHEMBL2778165 | 0.82 | CCR1 (0.48) | CCR1KCNH2TSHRLMNAHMOX1 | |
| SCHEMBL2777053 | 0.82 | CCR1 (0.48) | CCR1KCNH2 | |
| SCHEMBL2776334 | 0.82 | HMOX1 (0.53) | CCR1KCNH2LMNAHMOX1KMT2A | |
| SCHEMBL2776929 | 0.80 | LMNA (0.48) | CCR1KCNH2LMNAHMOX1KMT2A | |
| SCHEMBL6522911 | 0.80 | DPP4 (0.41) | LMNAEPHX2HMOX1USP30DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |