Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 13/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2778165 | 0.87 | CCR1 (0.48) | LMNAKMT2ACCR1KCNH2HMOX1 | |
| SCHEMBL2777053 | 0.87 | CCR1 (0.48) | CCR1KCNH2 | |
| SCHEMBL2776334 | 0.87 | HMOX1 (0.53) | LMNAKMT2ACCR1KCNH2HMOX1 | |
| SCHEMBL2779821 | 0.85 | CCR1 (0.47) | KMT2ACCR1KCNH2HMOX1 | |
| SCHEMBL2776253 | 0.84 | LIPE (0.45) | CCR1KCNH2HMOX1 | |
| SCHEMBL2776114 | 0.83 | ACACB (0.46) | LMNAKMT2ACCR1KCNH2HMOX1 | |
| SCHEMBL2774403 | 0.82 | KMT2A (0.43) | LMNAKMT2ACCR1KCNH2HMOX1 | |
| Hydrochloric Acid SCHEMBL2774333 | 0.81 | PIK3CD (0.44) | HMOX1GPR119 | |
| SCHEMBL2777506 | 0.81 | ALDH1A1 (0.44) | LMNACCR1KCNH2HMOX1 | |
| SCHEMBL2775650 | 0.80 | CCR1 (0.45) | LMNAKMT2ACCR1KCNH2HMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |