Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL958491 | 0.87 | KDM4E (0.55) | L3MBTL1CYP1A2GRM2SMN1; SMN2MAPT | |
| SCHEMBL12124009 | 0.85 | CYP1A2 (0.47) | L3MBTL1CYP1A2GRM2MAPTTDP1 | |
| SCHEMBL28106371 | 0.82 | PRKAG1 (0.44) | SMN1; SMN2HAO1KDM4EPRKAB2PRKAG1 | |
| SCHEMBL28253844 | 0.76 | PRKAG1 (0.47) | HAO1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL11919262 | 0.76 | PRKAG1 (0.51) | SMN1; SMN2MAPTLMNAHAO1KDM4E | |
| SCHEMBL24376424 | 0.75 | GRM2 (0.52) | L3MBTL1CYP1A2GRM2MAPTTDP1 | |
| SCHEMBL10209975 | 0.75 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL15730249 | 0.75 | L3MBTL1 (0.47) | L3MBTL1CYP1A2GRM2SMN1; SMN2MAPT | |
| SCHEMBL10210032 | 0.75 | ROCK2 (0.52) | L3MBTL1CYP1A2GRM2MAPTPRKAA1 | |
| SCHEMBL13375159 | 0.74 | PRKAG1 (0.63) | HAO1PRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101528708-B | Indazole derivatives useful as l-cpt1 inhibitors | HOFFMANN LA ROCHE | 2012-01-04 | — | — | CN | disclosed |
| CN-101528708-A | Indazole derivatives useful as L-CPT1 inhibitors | HOFFMANN LA ROCHE (CH) | 2009-09-09 | — | — | CN | disclosed |