Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL28093345 | 0.97 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL27413523 | 0.97 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL27838024 | 0.94 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL18730184 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL5964752 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL407467 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL164246 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL27650312 | 0.92 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL27413524 | 0.92 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL28093346 | 0.92 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDCA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109667067-A | A kind of barium calcium zirconate titanate base flexible piezoelectric composite fiber thin film and preparation method thereof and the flexible piezoelectric nano generator containing the film | 中国科学院过程工程研究所 | 2019-04-23 | — | — | CN | claimed |
| CN-105884350-B | A kind of barium calcium zirconate titanate lead-free piezoceramic material and preparation method thereof | 江苏大学 | 2019-04-02 | — | — | CN | claimed |
| CN-103427152-B | A kind of resonant antenna of adjustable electric sensibility reciprocal | GUIZHOU TAIGE TECHNOLOGY CO., LTD. (CN) | 2016-02-17 | — | — | CN | claimed |
| CN-101537494-B | Method for preparing nickel particle dispersion barium calcium zirconate titanate piezoelectric composite material | UNIV BEIJING SCIENCE & TECH | 2010-07-28 | — | — | CN | claimed |
| CN-101537494-A | Method for preparing nickel particle dispersion barium calcium zirconate titanate piezoelectric composite material | UNIV BEIJING SCIENCE & TECH | 2009-09-23 | — | — | CN | claimed |
| CN-110342932-A | A kind of preparation method of Er ions barium calcium zirconate titanate flexibility light-emitting film | 福州大学 | 2019-10-18 | — | — | CN | disclosed |
| CN-109667067-A | A kind of barium calcium zirconate titanate base flexible piezoelectric composite fiber thin film and preparation method thereof and the flexible piezoelectric nano generator containing the film | 中国科学院过程工程研究所 | 2019-04-23 | — | — | CN | disclosed |
| CN-105977374-B | A kind of barium calcium zirconate titanate film and its preparation method and application with seed layer | 聊城大学 | 2019-03-01 | — | — | CN | disclosed |
| CN-107244898-A | A kind of barium calcium zirconate titanate base leadless piezoelectric ceramics material of barium strontium titanate doping and preparation method thereof | 陕西师范大学 | 2017-10-13 | — | — | CN | disclosed |
| CN-104761260-B | Preparation method of (Ba＜x＞Ca＜1-x＞)(Ti＜y＞M＜1-y＞)O3 system piezoelectric ceramic material | 中国科学院福建物质结构研究所 | 2017-01-25 | — | — | CN | disclosed |
| CN-103427152-B | A kind of resonant antenna of adjustable electric sensibility reciprocal | GUIZHOU TAIGE TECHNOLOGY CO., LTD. (CN) | 2016-02-17 | — | — | CN | disclosed |
| CN-103427152-A | Inductance value adjustable resonant antenna | GUIZHOU TAIGE TECHNOLOGY CO LTD | 2013-12-04 | — | — | CN | disclosed |
| CN-203326100-U | Resonant antenna adjustable in inductance value | GUIZHOU TAIGE TECHNOLOGY CO LTD | 2013-12-04 | — | — | CN | disclosed |
| CN-101537494-B | Method for preparing nickel particle dispersion barium calcium zirconate titanate piezoelectric composite material | UNIV BEIJING SCIENCE & TECH | 2010-07-28 | — | — | CN | disclosed |
| CN-101537494-A | Method for preparing nickel particle dispersion barium calcium zirconate titanate piezoelectric composite material | UNIV BEIJING SCIENCE & TECH | 2009-09-23 | — | — | CN | disclosed |