Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL18730184 | 1.00 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL28093346 | 0.97 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL28093345 | 0.97 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL27757654 | 0.94 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL8736349 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL7519717 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL1319085 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL109123 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL210073 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 | |
| Phthalic Acid SCHEMBL4445698 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 936 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118978794-A | Preparation method of chain-extended nucleation modified poly (butylene succinate) | 华东理工大学 | 2024-11-19 | — | — | CN | claimed |
| EP-4387653-A1 | TISSUE MODIFIER AND USES THEREFOR | Foothill Saddleback Pty Ltd (AU) | 2024-06-26 | — | — | EP | claimed |
| WO-2023023776-A1 | TISSUE MODIFIER AND USES THEREFOR | Foothill Saddleback Pty Ltd (AU) | 2023-03-02 | — | — | WO | claimed |
| CN-110600655-B | Biaxially oriented aliphatic polyketone microporous membrane and preparation method and application thereof | 广东工业大学 | 2022-11-04 | — | — | CN | claimed |
| CN-111479869-B | Rubber composition and rubber crosslinked product | 日本瑞翁株式会社 | 2022-06-14 | — | — | CN | claimed |
| US-11236266-B2 | Breaking a fracturing fluid to prop a fracture in a subterranean formation | HALLIBURTON ENERGY SERVICES, INC. (US) | 2022-02-01 | — | — | US | claimed |
| CN-109365008-B | Calcium/aluminum ion exchange silica gel doped with rare earth elements and preparation method thereof | 广西新晶科技有限公司 | 2021-06-25 | — | — | CN | claimed |
| US-20210189223-A1 | FLUID FOR HYDRAULIC FRACTURING OF A SUBTERRANEAN FORMATION | HALLIBURTON ENERGY SERVICES, INC. | 2021-06-24 | — | — | US | claimed |
| CN-107162898-B | Method for preparing mixed phthalic acid and calcium salt thereof from PTA secondary residue | 常州大学 | 2021-01-29 | — | — | CN | claimed |
| CN-110577704-B | Method for improving performance of polypropylene-based thermoplastic vulcanizate | 北京化工大学 | 2021-01-19 | — | — | CN | claimed |
| WO-2003082734-A1 | SUPPORTED PEROXIDE COMPOSITIONS | GEO SPECIALTY CHEMICALS, INC. (US) | 2003-10-09 | — | — | WO | claimed |
| US-20030178600-A1 | Encapsulated peroxide compositions | GEO SPECIALTY CHEMICALS, INC. | 2003-09-25 | — | — | US | claimed |
| US-20030178599-A1 | Supported peroxides | GEO SPECIALTY CHEMICALS, INC. | 2003-09-25 | — | — | US | claimed |
| EP-0577059-B1 | Oxychlorination catalyst, process for preparing the catalyst and method of oxychlorination with use of the catalyst | SUMITOMO CHEMICAL CO (JP) | 1997-09-24 | — | — | EP | claimed |
| US-5334789-A | Oxychlorination of olefin or aromatic hydrocarbon with oxygen and hydrogen chloride in presence of catalyst containing compounds of palladium, copper, vanadium on carrier | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-08-02 | — | — | US | claimed |
| EP-0577059-A1 | Oxychlorination catalyst, process for preparing the catalyst and method of oxychlorination with use of the catalyst | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-01-05 | — | — | EP | claimed |
| US-5230936-A | Chlorinated polyethylene, a mercaptotriazine. crosslinking agent, acid acceptor | DAISCO CO., LTD. (JP) | 1993-07-27 | — | — | US | claimed |
| EP-0494839-A1 | A bedstead of springs made with compound materials | PIKOLIN, S.A. (ES) | 1992-07-15 | — | — | EP | claimed |
| US-4746698-A | OXIDE OR HYDROXIDE OF CALCIUM OR BARIUM | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-05-24 | — | — | US | claimed |
| EP-0221567-A2 | Method of preventing corrosion of apparatus for melt-processing polyarylene thioethers | Kureha Kagaku Kogyo Kabushiki Kaisha (also called: Kureha Chemical Industry Co. Ltd.) (JP) | 1987-05-13 | — | — | EP | claimed |