Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28780427 | 0.89 | PARP1 (0.51) | PARP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL27763531 | 0.88 | ALDH1A1 (0.52) | PARP1RAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL27742882 | 0.87 | DHODH (0.48) | PARP1RAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL27742923 | 0.86 | POLB (0.47) | PARP1RAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL27763530 | 0.86 | PARP1 (0.47) | PARP1RAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL27763517 | 0.86 | DHODH (0.45) | PARP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL27763518 | 0.85 | MMP2 (0.50) | PARP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL27742884 | 0.84 | SMN1; SMN2 (0.47) | PARP1RAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL27763514 | 0.81 | MMP2 (0.56) | PARP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL27742883 | 0.81 | MMP2 (0.50) | PARP1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101434601-A | 2-furyl-1H-benzimidazole-4-acidamide type derivative | UNIV SHANGHAI JIAOTONG (CN) | 2009-05-20 | — | — | CN | disclosed |