Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27742888 | 0.90 | KCNMA1 (0.47) | KCNMA1SMN1; SMN2NPC1HTTATM | |
| SCHEMBL27742884 | 0.90 | SMN1; SMN2 (0.47) | KCNMA1SMN1; SMN2NPC1HTTATM | |
| SCHEMBL27763523 | 0.84 | MAPT (0.51) | SMN1; SMN2NPC1HTTRAB9APKN1 | |
| SCHEMBL27763524 | 0.84 | DHODH (0.42) | ATMPKN1PKN2PARP1KMT2A | |
| SCHEMBL27763521 | 0.83 | MMP2 (0.53) | KCNMA1SMN1; SMN2NPC1HTTPKN1 | |
| SCHEMBL27742891 | 0.81 | DHODH (0.49) | SMN1; SMN2NPC1HTTRAB9APKN1 | |
| SCHEMBL27763507 | 0.80 | MMP2 (0.52) | SMN1; SMN2NPC1HTTRAB9APARP1 | |
| SCHEMBL27742870 | 0.80 | MMP2 (0.52) | SMN1; SMN2NPC1RAB9APKN1PKN2 | |
| SCHEMBL27763527 | 0.80 | MMP2 (0.52) | CYP1A2CYP2C19PARP1MMP2MMP9 | |
| SCHEMBL27763508 | 0.77 | MMP2 (0.44) | SMN1; SMN2NPC1RAB9APKN1PKN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101434601-A | 2-furyl-1H-benzimidazole-4-acidamide type derivative | UNIV SHANGHAI JIAOTONG (CN) | 2009-05-20 | — | — | CN | disclosed |