⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2751973 | 0.83 | ALDH1A1 (0.44) | — | |
| SCHEMBL1416299 | 0.75 | ESR2 (0.48) | — | |
| SCHEMBL2751422 | 0.71 | CA2 (0.50) | — | |
| SCHEMBL1416323 | 0.69 | CYP1A1 (0.50) | — | |
| SCHEMBL2185283 | 0.68 | FTO (0.40) | — | |
| SCHEMBL1416421 | 0.66 | APP (0.48) | — | |
| SCHEMBL3756 | 0.63 | — | — | |
| SCHEMBL63193 | 0.57 | ALDH1A1 (0.59) | — | |
| SCHEMBL1712973 | 0.57 | — | — | |
| SCHEMBL289777 | 0.56 | ALDH1A1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011072064-A1 | S PIRO [CHROMAN - 4, 4 ' - IMIDAZOL] ONES AS BETA - SECRETASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2011-06-16 | — | — | WO | claimed |
| EP-1897864-A1 | Anthracene derivatives and the use thereof for treating benign and malignant tumors | AEterna Zentaris GmbH (DE) | 2008-03-12 | — | — | EP | claimed |
| US-20080051463-A1 | ANTHRACENE COMPOUNDS AND THEIR USE FOR TREATING BENIGN AND MALIGNANT TUMOR DISORDERS | AETERNA ZENTARIS GMBH (DE) | 2008-02-28 | — | — | US | claimed |
| WO-2008015265-A1 | ANTHRACEN DERIVATIVES AND THEIR USE FOR THE TREATMENT OF BENIGN AND MALIGNANT TUMOROUS DISEASES | ÆTERNA ZENTARIS GMBH (DE) | 2008-02-07 | — | — | WO | claimed |
| US-4136100-A | BLUE-VIOLET TO GREEN-BLUE DYEINGS ON CELLULOSE TEXTILES | BASF AKTIENGESELLSCHAFT (DE) | 1979-01-23 | — | — | US | claimed |
| US-20240240226-A1 | FLUOROGENIC ASSAY FOR RAPID SCREENING OF BACTERIAL BETA-LACTAMASE ACTIVITY | UNIV LELAND STANFORD JUNIOR (US) | 2024-07-18 | — | — | US | disclosed |
| US-20240209254-A1 | OPTICAL ARTICLE, SPECTACLE LENS AND SPECTACLES | TOKUYAMA CORPORATION (JP) | 2024-06-27 | — | — | US | disclosed |
| CN-117881662-A | Herbicide malonamide containing monocyclic heteroaromatic ring | 巴斯夫欧洲公司 | 2024-04-12 | — | — | CN | disclosed |
| EP-4328636-A1 | OPTICAL ARTICLE, SPECTACLE LENS AND SPECTACLES | Tokuyama Corporation (JP) | 2024-02-28 | — | — | EP | disclosed |
| US-20240042068-A1 | CASPASE-3-TRIGGERED MOLECULAR SELF-ASSEMBLING PET PROBES AND USES THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2024-02-08 | — | — | US | disclosed |
| CN-117178209-A | Optical article, spectacle lens and spectacles | 株式会社德山 | 2023-12-05 | — | — | CN | disclosed |
| US-11679168-B2 | Caspase-3-triggered molecular self-assembling PET probes and uses thereof | THE BOARD OF TRUSTEES OF LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-06-20 | — | — | US | disclosed |
| EP-0163550-A2 | Mitomycin derivatives, preparation thereof and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1985-12-04 | — | — | EP | disclosed |
| EP-0035228-B1 | TETRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND ANTI-ULCER COMPOSITION CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-02 | — | — | EP | disclosed |
| EP-0022634-B1 | ACYLATED INDOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS AND DRUGS COMPRISING THEM | TEIJIN LIMITED (JP) | 1983-04-06 | — | — | EP | disclosed |
| US-4372953-A | Tetrazole derivatives, and anti-ulcer composition containing the same | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1983-02-08 | — | — | US | disclosed |
| EP-0035228-A1 | Tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-09 | — | — | EP | disclosed |
| EP-0022634-A1 | Acylated indole derivatives, processes for their preparation and pharmaceutical compositions and drugs comprising them | TEIJIN LIMITED (JP) | 1981-01-21 | — | — | EP | disclosed |
| US-4136100-A | BLUE-VIOLET TO GREEN-BLUE DYEINGS ON CELLULOSE TEXTILES | BASF AKTIENGESELLSCHAFT (DE) | 1979-01-23 | — | — | US | disclosed |
| US-4056544-A | Anthraquinone compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-01 | — | — | US | disclosed |