Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277654 | 0.87 | HPGD (0.56) | HPGDALDH1A1LMNACES2CES1 | |
| Methoxymethane SCHEMBL5593577 | 0.86 | HPGD (0.55) | HPGDALDH1A1LMNACES2CES1 | |
| SCHEMBL5051021 | 0.83 | SLC6A3 (0.49) | ALDH1A1LMNACES2CES1HTT | |
| SCHEMBL29384 | 0.82 | USP2 (0.52) | HPGDALDH1A1LMNACES2CES1 | |
| SCHEMBL27623521 | 0.81 | KAT6A (0.49) | HPGDALDH1A1LMNACES2CES1 | |
| Bicarbonate SCHEMBL31648960 | 0.81 | USP2 (0.51) | HPGDALDH1A1LMNACES2CES1 | |
| Methoxymethane SCHEMBL28122245 | 0.81 | USP2 (0.51) | HPGDALDH1A1LMNACES2CES1 | |
| Bicarbonate SCHEMBL1969232 | 0.81 | USP2 (0.51) | HPGDALDH1A1LMNACES2CES1 | |
| SCHEMBL28029106 | 0.81 | HPGD (0.47) | HPGDALDH1A1LMNACES2CES1 | |
| SCHEMBL3461505 | 0.80 | LMNA (0.55) | HPGDALDH1A1LMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772601-A1 | 4,5-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-05-14 | — | — | EP | disclosed |