Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | NADK | O95544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29328691 | 0.81 | ADORA2A (0.56) | LMNAPDE4DRXFP1ADORA3ADORA2A | |
| SCHEMBL29709122 | 0.81 | ADORA2A (0.56) | LMNAPDE4DRXFP1ADORA3ADORA2A | |
| SCHEMBL8146897 | 0.79 | PDE4D (0.63) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL8146893 | 0.79 | PDE4D (0.63) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL10266133 | 0.77 | PNP (0.48) | LMNAPNPALDH1A1ALBMAPK1 | |
| SCHEMBL12028110 | 0.77 | YTHDC1 (0.42) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL30694424 | 0.76 | LMNA (0.65) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL8124562 | 0.76 | LMNA (0.65) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL30149930 | 0.76 | LMNA (0.38) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL172618 | 0.76 | LMNA (0.65) | LMNAPDE4DPDE3APNPTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101410407-A | Substituted adenines and the uses thereof | ASTRAZENECA AB (SE) | 2009-04-15 | — | — | CN | disclosed |