Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AHCY | P23526 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30149926 | 0.89 | ERBB2 (0.32) | LMNANT5EHIF1AAHCYERBB2 | |
| SCHEMBL30149922 | 0.86 | LMNA (0.38) | LMNANT5EHIF1AALDH1A1ALB | |
| SCHEMBL19680287 | 0.81 | AHCY (0.54) | LMNAALDH1A1ALBMAPK1AHCY | |
| SCHEMBL3054167 | 0.76 | LMNA (0.58) | LMNANT5EHIF1AALDH1A1ALB | |
| SCHEMBL22862138 | 0.76 | LMNA (0.58) | LMNANT5EHIF1AALDH1A1ALB | |
| SCHEMBL2808298 | 0.76 | LMNA (0.58) | LMNANT5EHIF1AALDH1A1ALB | |
| SCHEMBL27767056 | 0.76 | LMNA (0.41) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL28646728 | 0.74 | LMNA (0.61) | LMNANT5EHIF1APNPTP53 | |
| SCHEMBL28644044 | 0.69 | NT5E (0.50) | LMNANT5EHIF1APNPRXFP1 | |
| SCHEMBL3047081 | 0.69 | LMNA (0.50) | LMNANT5EHIF1AALDH1A1ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023000708-A1 | POLYSUBSTITUTED PURINE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2023-01-26 | — | — | WO | disclosed |