SCHEMBL27767404

SCHEMBL27767404

NNS(=O)(=O)COc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.43
PTGS1 P23219 1/20 0.43
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
TAAR1 Q96RJ0 1/20 0.42
KCNA3 P22001 1/20 0.41
ALDH1A1 P00352 2/20 0.41
PGR P06401 1/20 0.41
MAPT P10636 1/20 0.41
ALOX15 P16050 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GAA P10253 1/20 0.41
AR P10275 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CA12 O43570 1/20 0.40
CA4 P22748 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728128 0.78 PGR (0.56) CA1CA2PGRMAPTSMN1; SMN2
SCHEMBL4905930 0.77 AR (0.44) PTGS1KCNA3ALDH1A1PGRMAPT
SCHEMBL27029743 0.77 CA1 (0.52) CA1CA2CA9TAAR1KCNA3
SCHEMBL1674268 0.76 KCNA3 (0.50) CA1CA2CA9TAAR1KCNA3
SCHEMBL9050973 0.74 ALDH1A1 (0.48) CA9ALDH1A1ARMEN1KMT2A
SCHEMBL17748432 0.74 KCNA3 (0.48) CA1CA2CA9TAAR1KCNA3
SCHEMBL465380 0.74 CA1 (0.65) CA1CA2CA9ALDH1A1PGR
SCHEMBL8062561 0.73 ALOX15 (0.47) CA1CA2CA9TAAR1KCNA3
SCHEMBL14873518 0.73 ALOX15 (0.39) CA1CA2KCNA3ALDH1A1PGR
SCHEMBL3089149 0.72 ALOX15 (0.50) CA1CA2CA9TAAR1KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104262447-A Preparation method of abiraterone acetate Jiang weng 2015-01-07 CN claimed
CN-103130766-B Piperine hydrazone or acylhydrazone or sulfonyl hydrazone derivative substances and application for preparing a botanical insecticide UNIV NORTHWEST A&F 2014-06-11 CN claimed
CN-103130766-A Piperine hydrazone or acylhydrazone or sulfonyl hydrazone derivative substances and application for preparing a botanical insecticide UNIV NORTHWEST A&F 2013-06-05 CN claimed
CN-105198683-A Preparation method of sulfuryl fluoride compound UNIV XINYANG NORMAL 2015-12-30 CN disclosed
CN-103130766-B Piperine hydrazone or acylhydrazone or sulfonyl hydrazone derivative substances and application for preparing a botanical insecticide UNIV NORTHWEST A&F 2014-06-11 CN disclosed
CN-103130766-A Piperine hydrazone or acylhydrazone or sulfonyl hydrazone derivative substances and application for preparing a botanical insecticide UNIV NORTHWEST A&F 2013-06-05 CN disclosed
CN-101602737-B Benzenesulfonyl quinoxaline compound and preparation method and application thereof UNIV ZHEJIANG 2011-09-14 CN disclosed
CN-101602737-A Benzenesulfonyl quinoxaline compound and preparation method and purposes UNIV ZHEJIANG (CN) 2009-12-16 CN disclosed