Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4012964 | 0.94 | KMT2A (0.44) | ALDH1A1KMT2AMEN1HPGDHSD17B10 | |
| Chloromethane SCHEMBL27592976 | 0.83 | CTSK (0.56) | ALDH1A1KMT2AMEN1PNMTCTSK | |
| Fluorobenzene SCHEMBL27858881 | 0.81 | HSD11B1 (0.47) | ALDH1A1KMT2AMEN1HSD17B10PNMT | |
| Chloromethane SCHEMBL27505309 | 0.81 | PSIP1 (0.54) | ALDH1A1KMT2AMEN1HSD17B10PNMT | |
| SCHEMBL2548723 | 0.79 | CTSK (0.59) | ALDH1A1KMT2AMEN1PNMTCTSK | |
| SCHEMBL7647205 | 0.79 | KMT2A (0.42) | ALDH1A1KMT2AMEN1PTGS2PAX8 | |
| SCHEMBL9820029 | 0.79 | NPC1 (0.48) | ALDH1A1KMT2AMEN1PNMTPSEN1 | |
| SCHEMBL3626870 | 0.79 | CTSK (0.59) | ALDH1A1KMT2AMEN1PNMTCTSK | |
| SCHEMBL12005105 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1HPGDHSD17B10 | |
| SCHEMBL1204934 | 0.76 | CA2 (0.52) | ALDH1A1KMT2AMEN1HPGDPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101547908-A | Heterocyclic derived metalloprotease inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2009-09-30 | — | — | CN | disclosed |