SCHEMBL27767693

SCHEMBL27767693

CC(=O)OCc1cc(O)c(C(O)c2ccc(CN)cc2)c(F)c1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PLG P00747 4/20 0.37
KLK1 P06870 3/20 0.37
KLK6 Q92876 3/20 0.37
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
KLKB1 P03952 3/20 0.35
CA2 P00918 1/20 0.35
TPSAB1 Q15661 2/20 0.33
BACE1 P56817 2/20 0.33
PRSS1 P07477 1/20 0.33
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4285479 0.89 ALDH1A1 (0.36) ALDH1A1CYP3A4CA2
SCHEMBL4292575 0.88 ALDH1A1 (0.37) ALDH1A1CYP3A4CA2KDM4E
SCHEMBL27767699 0.88 NPBWR1 (0.38) ALDH1A1CYP3A4SMN1; SMN2
SCHEMBL4285592 0.86 POLB (0.39) ALDH1A1CYP3A4SMN1; SMN2
SCHEMBL4292194 0.84 MAOB (0.40) ALDH1A1
SCHEMBL4279556 0.84 POLB (0.39) ALDH1A1SMN1; SMN2
SCHEMBL4281303 0.82 SLC5A1 (0.40) SMN1; SMN2
SCHEMBL28776649 0.80 ABAT (0.34) PLGKLK1KLK6ALDH1A1CYP3A4
SCHEMBL27767696 0.74 CYP4F2 (0.38) PLGKLK1KLK6KLKB1BACE1
SCHEMBL4283898 0.73 POLB (0.47) ALDH1A1CYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101472937-A Benzylphenylglucopyranoside Derivatives DAIICHI SANKYO CO LTD (JP) 2009-07-01 CN disclosed