SCHEMBL4281303

SCHEMBL4281303

CCCOc1ccc(C(O)c2c(O)cc(COC(C)=O)cc2F)cc1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC5A1 P13866 1/20 0.40
SLC5A2 P31639 1/20 0.40
ACACB O00763 9/20 0.39
ACACA Q13085 6/20 0.39
LTA4H P09960 1/20 0.39
MAOB P27338 2/20 0.39
CXCL12 P48061 1/20 0.39
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MAOA P21397 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4292194 0.91 MAOB (0.40) SLC5A1SLC5A2ACACBACACALTA4H
SCHEMBL4285592 0.87 POLB (0.39) SLC5A1SLC5A2MAOBLMNASMN1; SMN2
SCHEMBL4285479 0.85 ALDH1A1 (0.36) MAOBLMNA
SCHEMBL4279556 0.85 POLB (0.39) ACACBACACAMAOBSMN1; SMN2
SCHEMBL4292575 0.84 ALDH1A1 (0.37) SLC5A1SLC5A2MAOBLMNA
SCHEMBL27767699 0.84 NPBWR1 (0.38) MAOBLMNAL3MBTL1SMN1; SMN2
SCHEMBL27767693 0.82 PLG (0.37) SMN1; SMN2
SCHEMBL4279693 0.79 SLC5A1 (0.45) SLC5A1SLC5A2ACACBLTA4HMAOB
SCHEMBL4292204 0.79 ALDH1A1 (0.40) SLC5A1SLC5A2ACACBACACALTA4H
SCHEMBL4284273 0.79 SLC5A1 (0.47) SLC5A1SLC5A2LTA4HMAOBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101472937-A Benzylphenylglucopyranoside Derivatives DAIICHI SANKYO CO LTD (JP) 2009-07-01 CN disclosed
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 SLC5A1 1/4885SLC5A2 2/4885ACACB 1570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.