SCHEMBL4285592

SCHEMBL4285592

COc1ccc(C(O)c2c(O)cc(COC(C)=O)cc2F)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
CYP3A4 P08684 3/20 0.38
MAPT P10636 2/20 0.38
PPARG P37231 1/20 0.38
FFAR1 O14842 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
MCL1 Q07820 1/20 0.37
EDNRA P25101 1/20 0.37
SLC5A1 P13866 1/20 0.36
SLC5A2 P31639 1/20 0.36
MAOB P27338 1/20 0.36
APP P05067 1/20 0.36
CYP2C19 P33261 1/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
ALDH1A1 P00352 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4292194 0.89 MAOB (0.40) POLBMEN1KMT2AMAPTPPARG
SCHEMBL4279556 0.89 POLB (0.39) POLBMAOBALDH1A1SMN1; SMN2
SCHEMBL4292575 0.88 ALDH1A1 (0.37) POLBMEN1KMT2ACYP3A4MAPT
SCHEMBL27767699 0.88 NPBWR1 (0.38) CYP3A4MAPTMAOBLMNAALDH1A1
SCHEMBL4287172 0.87 NPBWR1 (0.41) POLBMEN1KMT2ACYP3A4MAPT
SCHEMBL4285479 0.87 ALDH1A1 (0.36) POLBMEN1KMT2ACYP3A4MAOB
SCHEMBL4283898 0.87 POLB (0.47) POLBMEN1KMT2ACYP3A4MAPT
SCHEMBL4281303 0.87 SLC5A1 (0.40) SLC5A1SLC5A2MAOBLMNASMN1; SMN2
SCHEMBL27767693 0.86 PLG (0.37) CYP3A4ALDH1A1SMN1; SMN2
SCHEMBL4291912 0.77 NFKB1 (0.42) MEN1KMT2ACYP3A4MAPTNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 POLB 4872/4885MEN1 3776/4885KMT2A 1397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.