SCHEMBL4285479

SCHEMBL4285479

CCc1ccc(C(O)c2c(O)cc(COC(C)=O)cc2F)cc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
CYP3A4 P08684 1/20 0.36
LMNA P02545 2/20 0.33
CA2 P00918 1/20 0.33
EGFR P00533 1/20 0.33
TRPA1 O75762 1/20 0.33
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
KMT2A Q03164 1/20 0.32
SAE1 Q9UBE0 1/20 0.32
UBA2 Q9UBT2 1/20 0.32
GAA P10253 2/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27767693 0.89 PLG (0.37) ALDH1A1CYP3A4CA2
SCHEMBL27767699 0.89 NPBWR1 (0.38) ALDH1A1CYP3A4LMNAEGFRMAOB
SCHEMBL4292575 0.89 ALDH1A1 (0.37) ALDH1A1CYP3A4LMNACA2MEN1
SCHEMBL4292194 0.87 MAOB (0.40) ALDH1A1LMNAMEN1POLBKMT2A
SCHEMBL4285592 0.87 POLB (0.39) ALDH1A1CYP3A4LMNAMEN1POLB
SCHEMBL4281303 0.85 SLC5A1 (0.40) LMNAMAOB
SCHEMBL4279556 0.85 POLB (0.39) ALDH1A1POLBMAOB
SCHEMBL4285331 0.81 TRPA1 (0.39) ALDH1A1LMNATRPA1
SCHEMBL4286864 0.78 IDH1 (0.41) ALDH1A1CYP3A4LMNACA2TRPA1
SCHEMBL4286671 0.76 ALDH1A1 (0.38) ALDH1A1CYP3A4CA2TRPA1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-05-28 US disclosed
EP-2048150-A1 BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2009-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137499-A1 BENZYLPHENYL GLUCOPYRANOSIDE DERIVATIVE SLC5A1, SLC5A2, SLC2A1 ALDH1A1 896/4885CYP3A4 534/4885LMNA 3975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.