Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL543429 | 0.85 | RORC (0.40) | — | |
| SCHEMBL7586432 | 0.84 | CYP11B2 (0.45) | MAOAKDM4EALDH1A1GAAGLA | |
| SCHEMBL343467 | 0.78 | XDH (0.52) | — | |
| SCHEMBL343950 | 0.78 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDGAALMNA | |
| SCHEMBL17372804 | 0.78 | HTR7 (0.40) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL28481204 | 0.78 | ALDH1A1 (0.39) | MAOAMAOBKDM4EALDH1A1HPGD | |
| SCHEMBL10123878 | 0.77 | SLC22A12 (0.38) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL343003 | 0.77 | PPM1B (0.40) | — | |
| SCHEMBL10123766 | 0.77 | RORC (0.46) | KMT2AMEN1FLT3 | |
| SCHEMBL27897608 | 0.77 | KDM4E (0.38) | MAOAMAOBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101486710-B | Method for synthesizing 3-halogenated indolizine compound | SHANGHAI INST ORGANIC CHEM | 2011-04-06 | — | — | CN | disclosed |
| CN-101486710-A | Method for synthesizing 3-halogenated indolizine compound | SHANGHAI INST ORGANIC CHEM (CN) | 2009-07-22 | — | — | CN | disclosed |