Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | WNT3A | P56704 | 1/20 | 0.50 |
| ▸ | ATP4A | P20648 | 1/20 | 0.47 |
| ▸ | ATP4B | P51164 | 1/20 | 0.47 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2395281 | 0.87 | ATP4A (0.49) | KMT2AATP4AATP4BELOVL1HTT | |
| SCHEMBL3613607 | 0.85 | LTA4H (0.59) | KMT2AATP4AATP4BELOVL1MAPT | |
| SCHEMBL27768248 | 0.85 | ATP4A (0.56) | AOC3KMT2AATP4AATP4BELOVL1 | |
| SCHEMBL3607861 | 0.84 | ABL1 (0.47) | AOC3KMT2AWNT3AATP4AATP4B | |
| SCHEMBL3594785 | 0.84 | MAPT (0.65) | KMT2AATP4AATP4BMAPTLMNA | |
| SCHEMBL3604799 | 0.84 | ALOX5 (0.61) | AOC3KMT2AWNT3AATP4AATP4B | |
| SCHEMBL3603727 | 0.82 | GSTO1 (0.60) | KMT2AMAPTLMNAHTTALDH1A1 | |
| SCHEMBL3598628 | 0.82 | MAPT (0.58) | KMT2AELOVL1MAPTLMNAHTT | |
| SCHEMBL30660071 | 0.82 | MAPT (0.48) | AOC3KMT2AWNT3AATP4AATP4B | |
| SCHEMBL3602636 | 0.82 | ABL1 (0.65) | KMT2AMAPTLMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101466692-A | Thiazol-guanidine derivatives useful as a (beta) - related pathologies | ASTRAZENECA AB (SE) | 2009-06-24 | — | — | CN | claimed |
| CN-101466692-A | Thiazol-guanidine derivatives useful as a (beta) - related pathologies | ASTRAZENECA AB (SE) | 2009-06-24 | — | — | CN | disclosed |