Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19604253 | 0.80 | ABCB1 (0.50) | ABCB1KDM4ETSHRHSD17B10MEN1 | |
| SCHEMBL3029800 | 0.77 | HCRTR1 (0.62) | ABCB1KDM4ETSHRHSD17B10MEN1 | |
| SCHEMBL27828777 | 0.77 | SSTR4 (0.48) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL2776838 | 0.77 | ABCB1 (0.50) | ABCB1KDM4ETSHRHSD17B10MEN1 | |
| SCHEMBL12572402 | 0.76 | PTGS2 (0.65) | ABCB1KDM4ETSHRHSD17B10MEN1 | |
| SCHEMBL13020272 | 0.74 | TSHR (0.47) | ABCB1KDM4ETSHRHSD17B10MEN1 | |
| SCHEMBL7645232 | 0.74 | KDM4E (0.58) | ABCB1KDM4ETSHRHSD17B10MEN1 | |
| SCHEMBL28812389 | 0.73 | ABCB1 (0.55) | ABCB1KDM4ETSHRHSD17B10MEN1 | |
| SCHEMBL7823764 | 0.73 | L3MBTL1 (0.64) | ABCB1KDM4ETSHRHSD17B10MEN1 | |
| SCHEMBL4208261 | 0.73 | ABCB1 (0.52) | ABCB1KDM4ETSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161266-A1 | Benzofuran derivatives as orexin receptor antagonists | EVOTEC Neurosciences GmbH (DE) | 2010-03-10 | — | — | EP | disclosed |