Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27557322 | 0.94 | TSHR (0.47) | TSHRLMNAALDH1A1TP53CYP3A4 | |
| SCHEMBL28093002 | 0.88 | LMNA (0.47) | LMNAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL2831628 | 0.85 | TSHR (0.49) | TSHRLMNAALDH1A1TP53CYP3A4 | |
| SCHEMBL547242 | 0.82 | ALDH1A1 (0.42) | LMNAALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL12851497 | 0.82 | MEN1 (0.51) | TSHRLMNAALDH1A1MAPK1NPC1 | |
| SCHEMBL93317 | 0.82 | MEN1 (0.51) | TSHRLMNAALDH1A1MAPK1NPC1 | |
| SCHEMBL26673753 | 0.82 | THRB (0.45) | TSHRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4197206 | 0.81 | HDAC1 (0.46) | POLBPPARG | |
| SCHEMBL27883613 | 0.80 | KDM4E (0.46) | TSHRALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4094428 | 0.80 | FAAH (0.49) | TSHRLMNAALDH1A1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107440819-A | Change the method for the refractive index of optical material and resulting optical visual device | 罗切斯特大学 | 2017-12-08 | — | — | CN | disclosed |
| CN-103889368-B | Method for changing refractive index of optical material and optical visual device obtained by same | 罗切斯特大学 | 2017-04-12 | — | — | CN | disclosed |
| CN-102065795-B | Intraocular lens with photosensitizer and method for modifying the refractive index of the lens | BAUSCH & LOMB | 2014-09-10 | — | — | CN | disclosed |
| CN-103889368-A | Method for changing refractive index of optical material and optical visual device obtained by same | BAUSCH & LOMB | 2014-06-25 | — | — | CN | disclosed |
| CN-101489509-B | Method for changing refractive index of optical material and optical device | BAUSCH & LOMB | 2013-03-13 | — | — | CN | disclosed |
| CN-102065795-A | Intraocular lens with photosensitizer and method for modifying the refractive index of the lens | BAUSCH & LOMB | 2011-05-18 | — | — | CN | disclosed |
| CN-101489509-A | Optical materials and methods for changing refractive index | BAUSCH & LOMB (US) | 2009-07-22 | — | — | CN | disclosed |