Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 3/20 | 0.56 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18195379 | 0.85 | ALDH1A1 (0.54) | HSD17B10KDM4EMAPTRAB9ATSHR | |
| SCHEMBL2179717 | 0.85 | TRPM8 (0.58) | CDC7DBF4HSD17B10KDM4EMAPT | |
| SCHEMBL26524147 | 0.84 | KMT2A (0.56) | HSD17B10MAPK1KDM4EMAPTRAB9A | |
| SCHEMBL17212202 | 0.83 | CDC7 (0.62) | CDC7DBF4HSD17B10KDM4EKMT2A | |
| SCHEMBL1680202 | 0.82 | RAB9A (0.59) | HSD17B10KDM4EMAPTRAB9ATSHR | |
| SCHEMBL22617521 | 0.80 | CDC7 (0.42) | CDC7DBF4HSD17B10KDM4ERAB9A | |
| SCHEMBL1638364 | 0.80 | CDC7 (0.73) | CDC7DBF4HSD17B10MAPK1KDM4E | |
| SCHEMBL27768803 | 0.80 | KDM4E (0.58) | HSD17B10KDM4EMAPTRAB9ATSHR | |
| SCHEMBL1423803 | 0.80 | HSD17B10 (0.49) | CDC7DBF4HSD17B10MAPK1KDM4E | |
| SCHEMBL255828 | 0.80 | ALDH1A1 (0.64) | HSD17B10KDM4EMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2586311-B1 | Heterocyclic compounds as pest controllers | BAYER CROPSCIENCE AG (DE) | 2016-12-14 | — | — | EP | disclosed |
| EP-2730569-B1 | New amides and thioamides as pest control agents | BAYER CROPSCIENCE AG (DE) | 2016-11-30 | — | — | EP | disclosed |
| US-20160316755-A1 | Novel Heteroaromatic Amides and Thioamides as Pesticides | BAYER CROPSCIENCE AG (DE) | 2016-11-03 | — | — | US | disclosed |
| US-20160316755-A1 | Novel Heteroaromatic Amides and Thioamides as Pesticides | BAYER CROPSCIENCE AG (DE) | 2016-11-03 | — | — | US | disclosed |
| US-20160316755-A1 | Novel Heteroaromatic Amides and Thioamides as Pesticides | BAYER CROPSCIENCE AG (DE) | 2016-11-03 | — | — | US | disclosed |
| US-9451775-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-27 | — | — | US | disclosed |
| US-9451775-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-27 | — | — | US | disclosed |
| US-9451775-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-27 | — | — | US | disclosed |
| US-9428487-B2 | Heteroaromatic amides and thioamides as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-08-30 | — | — | US | disclosed |
| US-9428487-B2 | Heteroaromatic amides and thioamides as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-08-30 | — | — | US | disclosed |
| EP-2583557-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| EP-2583556-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| US-20110212949-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG | 2011-09-01 | — | — | US | disclosed |
| US-20110212949-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG | 2011-09-01 | — | — | US | disclosed |
| US-20110212949-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG | 2011-09-01 | — | — | US | disclosed |
| US-20110098287-A1 | Novel Heteroaromatic Amides And Thioamides As Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-04-28 | — | — | US | disclosed |
| US-20110098287-A1 | Novel Heteroaromatic Amides And Thioamides As Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-04-28 | — | — | US | disclosed |
| US-20110098287-A1 | Novel Heteroaromatic Amides And Thioamides As Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-04-28 | — | — | US | disclosed |
| WO-2010006713-A2 | HETEROCYCLIC COMPOUNDS USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2010-01-21 | — | — | WO | disclosed |
| WO-2009149858-A1 | NOVEL HETEROAROMATIC AMIDES AND THIOAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2009-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160316755-A1 | Novel Heteroaromatic Amides and Thioamides as Pesticides | AADAC, DDT, TST | CDC7 4359/4885DBF4 222/4885HSD17B10 2938/4885 |
| US-20110212949-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, PTMS | CDC7 2413/4885DBF4 184/4885HSD17B10 624/4885 |
| US-20110098287-A1 | Novel Heteroaromatic Amides And Thioamides As Pesticides | AADAC, DDT, TST | CDC7 4359/4885DBF4 222/4885HSD17B10 2938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.