Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TAS2R10 | Q9NYW0 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7103936 | 0.93 | CES2 (0.45) | CES2CES1DNM1POLBALPL | |
| Oxalic Acid SCHEMBL27769823 | 0.90 | DNM1 (0.47) | CES2CES1DNM1POLBALPL | |
| Oxalic Acid SCHEMBL27769830 | 0.89 | DNM1 (0.44) | CES2CES1DNM1POLBMEN1 | |
| SCHEMBL991989 | 0.87 | DNM1 (0.52) | DNM1MEN1KMT2ATP53MAPK1 | |
| Hydrogen Sulfide SCHEMBL5999599 | 0.87 | DNM1 (0.52) | DNM1MEN1KMT2ATP53MAPK1 | |
| Oxalic Acid SCHEMBL1050278 | 0.85 | LMNA (0.49) | CES2CES1POLBALPLALPG | |
| Hydrogen Sulfide SCHEMBL5999597 | 0.85 | DNM1 (0.50) | DNM1MEN1KMT2ATP53MAPK1 | |
| Hydrochloric Acid SCHEMBL239800 | 0.85 | KDM4E (0.54) | DNM1MEN1KMT2ATP53MAPK1 | |
| Hydrochloric Acid SCHEMBL28683171 | 0.85 | DNM1 (0.50) | DNM1MEN1KMT2ATP53MAPK1 | |
| Iodide SCHEMBL236084 | 0.85 | DNM1 (0.50) | DNM1MEN1KMT2ATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101633673-B | Method for preparing oxaliplatin | Nanjing pharmaceutical factory co ltd | 2012-01-11 | — | — | CN | disclosed |
| CN-101633673-A | Method for preparing oxaliplatin | Nanjing pharmaceutical factory | 2010-01-27 | — | — | CN | disclosed |