Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27991279 | 0.87 | MGLL (0.51) | MGLLHSD11B1SLC18A3KMT2APOLB | |
| SCHEMBL27597017 | 0.86 | ELANE (0.46) | MGLLHSD11B1KMT2AMEN1LMNA | |
| SCHEMBL28017484 | 0.85 | MEN1 (0.43) | MGLLSLC18A3KMT2AMEN1MAPK1 | |
| SCHEMBL28024239 | 0.82 | BRD4 (0.42) | KMT2ARAB9ANPC1RECQLSMN1; SMN2 | |
| SCHEMBL4192895 | 0.77 | RORC (0.48) | MGLLHSD11B1KMT2APOLBMEN1 | |
| SCHEMBL27958057 | 0.76 | HTT (0.43) | KMT2APOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27629058 | 0.75 | NAMPT (0.41) | SLC18A3KMT2APOLBMAPT | |
| SCHEMBL4190126 | 0.75 | MGLL (0.51) | MGLLHSD11B1SLC18A3KMT2APOLB | |
| SCHEMBL27758338 | 0.73 | HSD11B1 (0.57) | MGLLHSD11B1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL3604589 | 0.72 | KMT2A (0.54) | MGLLHSD11B1SLC18A3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101454328-A | Novel mch receptor antagonists | LILLY CO ELI (US) | 2009-06-10 | — | — | CN | disclosed |