Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | METAP2 | P50579 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12659878 | 0.90 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL9618720 | 0.81 | ALDH1A1 (0.74) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL16020385 | 0.80 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL11421681 | 0.79 | ACLY (0.61) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL11412878 | 0.79 | MEN1 (0.58) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL14398640 | 0.79 | MEN1 (0.60) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL6181264 | 0.79 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL1466906 | 0.78 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL27930218 | 0.78 | SLC40A1 (0.63) | MEN1KMT2AMETAP2L3MBTL1ATM | |
| SCHEMBL15822907 | 0.78 | ALDH1A1 (0.68) | MEN1KMT2AALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646647-A | New methylenebisphenyl compounds useful in the treatment of inflammation | BIOLIPOX AB SE | 2010-02-10 | — | — | CN | disclosed |