Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27770376 | 0.89 | HTT (0.51) | HTTALDH1A1RAB9ALMNANPC1 | |
| SCHEMBL1202552 | 0.82 | HTT (0.61) | HTTALDH1A1RAB9ALMNANPC1 | |
| SCHEMBL4622917 | 0.82 | THRB (0.48) | ALDH1A1CYP1A2CYP2C19KMT2AHPGD | |
| SCHEMBL22129790 | 0.81 | PLA2G1B (0.56) | HTTLMNACYP2C19KMT2APLA2G1B | |
| SCHEMBL1240060 | 0.78 | ALDH1A1 (0.51) | HTTALDH1A1RAB9ALMNANPC1 | |
| SCHEMBL28069456 | 0.77 | PLA2G1B (0.62) | ALDH1A1RAB9ALMNANPC1POLB | |
| SCHEMBL17278163 | 0.75 | PLA2G1B (0.52) | HTTALDH1A1RAB9ALMNACYP2C19 | |
| SCHEMBL2553685 | 0.74 | HTT (0.65) | HTTALDH1A1RAB9ALMNANPC1 | |
| SCHEMBL21776624 | 0.73 | LMNA (0.49) | HTTALDH1A1RAB9ALMNANPC1 | |
| SCHEMBL8338756 | 0.73 | LMNA (0.49) | HTTALDH1A1RAB9ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101495120-A | Composition for induction or inhibition of stem cell differentiation | CHOONGWAE PHARMA CORP (KR) | 2009-07-29 | — | — | CN | disclosed |