Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27770375 | 0.89 | HTT (0.54) | HTTALDH1A1RAB9ALMNANPC1 | |
| SCHEMBL402730 | 0.83 | CYP2D6 (0.47) | ALDH1A1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL1202552 | 0.79 | HTT (0.61) | HTTALDH1A1RAB9ALMNANPC1 | |
| SCHEMBL1240060 | 0.76 | ALDH1A1 (0.51) | HTTALDH1A1RAB9ALMNANPC1 | |
| SCHEMBL22129790 | 0.73 | PLA2G1B (0.56) | HTTLMNAKMT2ACYP2C19PLA2G1B | |
| SCHEMBL4622917 | 0.71 | THRB (0.48) | ALDH1A1KMT2ACYP1A2CYP2C19HPGD | |
| SCHEMBL2553685 | 0.71 | HTT (0.65) | HTTALDH1A1RAB9ALMNANPC1 | |
| SCHEMBL9509093 | 0.71 | LDHA (0.44) | ALDH1A1LMNACYP2C19 | |
| SCHEMBL21776624 | 0.70 | LMNA (0.49) | HTTALDH1A1RAB9ALMNANPC1 | |
| SCHEMBL8338756 | 0.70 | LMNA (0.49) | HTTALDH1A1RAB9ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101495120-A | Composition for induction or inhibition of stem cell differentiation | CHOONGWAE PHARMA CORP (KR) | 2009-07-29 | — | — | CN | disclosed |