Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730411 | 0.81 | GRM6 (0.49) | GRM6SLC7A5ALDH1A1KDM4EGLA | |
| SCHEMBL27770533 | 0.79 | GRM6 (0.41) | GRM6SLC7A5ALDH1A1KDM4EGLA | |
| SCHEMBL17054139 | 0.76 | GRM6 (0.39) | GRM6SLC7A5ALDH1A1KDM4EGLA | |
| SCHEMBL976497 | 0.76 | MMP2 (0.47) | GRM6SLC7A5ALDH1A1KDM4EGLA | |
| SCHEMBL7870163 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL2718238 | 0.75 | CA12 (0.48) | GRM6SLC7A5ALDH1A1KDM4EGLA | |
| SCHEMBL16680460 | 0.75 | THRB (0.40) | GRM6SLC7A5ALDH1A1KDM4EGLA | |
| SCHEMBL4644479 | 0.74 | GRM6 (0.43) | GRM6SLC7A5ALDH1A1KDM4EGLA | |
| SCHEMBL6830109 | 0.74 | POLB (0.45) | GRM6SLC7A5ALDH1A1KDM4EGLA | |
| SCHEMBL10982569 | 0.74 | GRM6 (0.43) | GRM6SLC7A5ALDH1A1KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067928-A4 | METHODS FOR INHIBITING MRP1 | LILLY CO ELI (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-1067928-A1 | METHODS FOR INHIBITING MRP1 | ELI LILLY AND COMPANY (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999051228-A1 | METHODS FOR INHIBITING MRP1 | ELI LILLY AND COMPANY (US) | 1999-10-14 | — | — | WO | disclosed |