SCHEMBL16680460

SCHEMBL16680460

C=CC(=O)Oc1cccc(N)c1C(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.40
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 2/20 0.40
GLA P06280 2/20 0.40
GAA P10253 2/20 0.40
MAPT P10636 2/20 0.40
HPGD P15428 2/20 0.40
HIF1A Q16665 2/20 0.40
THRA P10827 1/20 0.39
GRM6 O15303 1/20 0.38
TYMS P04818 1/20 0.34
TSHR P16473 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
SLC7A5 Q01650 1/20 0.32
HSD17B10 Q99714 2/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27770533 0.83 GRM6 (0.41) THRBALDH1A1KDM4EGLAGAA
SCHEMBL17054139 0.82 GRM6 (0.39) THRBALDH1A1KDM4EGLAGAA
SCHEMBL16681024 0.82 THRB (0.39) THRBALDH1A1KDM4EGLAGAA
SCHEMBL2730411 0.79 GRM6 (0.49) THRBALDH1A1KDM4EGLAGAA
SCHEMBL27368260 0.77 KDM4E (0.45) THRBALDH1A1KDM4EMAPTHPGD
SCHEMBL7861823 0.75 GRM6 (0.39) THRBALDH1A1KDM4EGLAGAA
SCHEMBL1064807 0.75 KDM4E (0.42) THRBALDH1A1KDM4EGLAGAA
SCHEMBL3291662 0.74 THRB (0.49) THRBALDH1A1KDM4EGAAMAPT
SCHEMBL9707104 0.74 THRB (0.47) THRBALDH1A1KDM4EMAPTHPGD
SCHEMBL2718238 0.73 CA12 (0.48) THRBALDH1A1KDM4EGLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9128378-B2 Forming conductive metal patterns with reactive polymers EASTMAN KODAK COMPANY (US) 2015-09-08 US disclosed
US-20150125667-A1 FORMING CONDUCTIVE METAL PATTERNS WITH REACTIVE POLYMERS BANK OF AMERICA, N.A., AS AGENT 2015-05-07 US disclosed