Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27792464 | 0.86 | KCNMA1 (0.55) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL27792398 | 0.86 | KMT2A (0.55) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL27792371 | 0.79 | ALDH1A1 (0.60) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL27792367 | 0.72 | MEN1 (0.60) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL24142977 | 0.72 | MEN1 (0.61) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL27771252 | 0.71 | KCNMA1 (0.65) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL4286409 | 0.71 | MAPT (0.57) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL27792404 | 0.71 | MEN1 (0.70) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL12021436 | 0.71 | GCK (0.55) | NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL22348661 | 0.70 | NPC1 (0.72) | MAPTALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101648919-A | 3-substituted salicylamide compound, preparation method, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2010-02-17 | — | — | CN | disclosed |