Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | FADS1 | O60427 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GCK | P35557 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27792464 | 0.85 | KCNMA1 (0.55) | KCNMA1MAOBMAOAALDH1A1KMT2A | |
| SCHEMBL27792398 | 0.85 | KMT2A (0.55) | KCNMA1MAOBMAOAALDH1A1KMT2A | |
| SCHEMBL27792361 | 0.82 | KCNMA1 (0.66) | KCNMA1MAOBMAOAFADS1ALDH1A1 | |
| SCHEMBL27771283 | 0.81 | FADS1 (0.67) | MAOBMAOAFADS1NPC1RAB9A | |
| SCHEMBL14886072 | 0.80 | KCNMA1 (1.00) | KCNMA1ALDH1A1KMT2AMEN1GCK | |
| SCHEMBL7347439 | 0.76 | MAOB (0.67) | MAOBMAOAFADS1RXRARXRB | |
| SCHEMBL27771260 | 0.76 | FADS1 (0.52) | KCNMA1MAOBMAOAFADS1KMT2A | |
| SCHEMBL7348486 | 0.76 | MAOB (0.83) | MAOBMAOARXRARXRBRXRG | |
| SCHEMBL27771246 | 0.72 | FADS1 (0.57) | MAOBMAOAFADS1ALDH1A1KMT2A | |
| SCHEMBL27771271 | 0.72 | GCK (0.59) | MAOBMAOAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101648919-A | 3-substituted salicylamide compound, preparation method, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2010-02-17 | — | — | CN | disclosed |