Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | MITF | O75030 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | GFER | P55789 | 1/20 | 0.69 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2596926 | 1.00 | ALDH1A1 (0.69) | ALDH1A1MITFSMN1; SMN2RAB9AHTT | |
| Hydrochloric Acid SCHEMBL2551763 | 0.98 | ALDH1A1 (0.72) | ALDH1A1MITFSMN1; SMN2RAB9AHTT | |
| SCHEMBL12282101 | 0.98 | MITF (0.71) | ALDH1A1MITFSMN1; SMN2RAB9AHTT | |
| SCHEMBL7592795 | 0.98 | MITF (0.71) | ALDH1A1MITFSMN1; SMN2RAB9AHTT | |
| SCHEMBL25107503 | 0.95 | MITF (0.67) | ALDH1A1MITFSMN1; SMN2RAB9AHTT | |
| SCHEMBL11222652 | 0.87 | MITF (0.66) | ALDH1A1MITFSMN1; SMN2RAB9AHTT | |
| SCHEMBL6321267 | 0.85 | SMN1; SMN2 (0.94) | ALDH1A1MITFSMN1; SMN2RAB9AHTT | |
| SCHEMBL17616735 | 0.85 | MITF (0.68) | ALDH1A1MITFSMN1; SMN2RAB9AHTT | |
| SCHEMBL1683001 | 0.84 | LMNA (0.64) | ALDH1A1MITFSMN1; SMN2RAB9AHTT | |
| SCHEMBL9911024 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MITFSMN1; SMN2RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101610813-A | Quinuclidinol derivatives as muscarinic receptor antagonist | ASTRAZENECA AB (SE) | 2009-12-23 | — | — | CN | disclosed |