Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222652 | 0.98 | MITF (0.66) | MITFSMN1; SMN2ALDH1A1RAB9AHTT | |
| SCHEMBL12282101 | 0.86 | MITF (0.71) | MITFSMN1; SMN2ALDH1A1RAB9AHTT | |
| SCHEMBL7592795 | 0.86 | MITF (0.71) | MITFSMN1; SMN2ALDH1A1RAB9AHTT | |
| SCHEMBL27772020 | 0.85 | ALDH1A1 (0.69) | MITFSMN1; SMN2ALDH1A1RAB9AHTT | |
| SCHEMBL2596926 | 0.85 | ALDH1A1 (0.69) | MITFSMN1; SMN2ALDH1A1RAB9AHTT | |
| SCHEMBL684723 | 0.84 | NTSR1 (0.59) | MITFSMN1; SMN2ALDH1A1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL2551763 | 0.83 | ALDH1A1 (0.72) | MITFSMN1; SMN2ALDH1A1RAB9AHTT | |
| SCHEMBL25107503 | 0.83 | MITF (0.67) | MITFSMN1; SMN2ALDH1A1RAB9AHTT | |
| SCHEMBL2552200 | 0.83 | ALDH1A1 (0.62) | MITFSMN1; SMN2ALDH1A1RAB9AHTT | |
| SCHEMBL1683001 | 0.83 | LMNA (0.64) | MITFSMN1; SMN2ALDH1A1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512147-B2 | Organoboron compounds and methods of making organoboron compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-12-06 | — | — | US | disclosed |
| US-20160083402-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083402-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | NDC1, ELOC, UGT2B7 | MITF 3166/4885SMN1; SMN2 1952/4885ALDH1A1 1921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.